Trichloroacetic Acid (TCA)
Trichloroacetic Acid (TCA) is a strong, medical-grade acid used in dermatology and cosmetic procedures to perform chemical peels. It is a derivative of acetic acid (similar to vinegar) with three chlorine atoms added to increase its potency and depth of action. TCA works by causing controlled chemical injury to the skin, which leads to exfoliation of damaged outer layers and stimulates new skin growth and collagen production underneath.
TCA is available in various strengths, usually ranging from 10% to 50%, and is used for different levels of peeling — from superficial to deep. It is commonly used to treat fine lines, pigmentation, acne scars, and sun-damaged skin, and may also be used to remove certain skin lesions. TCA peels should be performed by trained professionals, especially at medium to high concentrations, due to the risk of irritation, burns, or complications.
❓What It Does in Skincare
- Performs chemical exfoliation by breaking down the protein bonds in the skin’s outer layers, causing peeling and regeneration.
- Stimulates new collagen production and encourages smoother, firmer, and more youthful-looking skin.
- Reduces the appearance of fine lines, wrinkles, and hyperpigmentation such as sunspots and melasma.
- Improves texture and tone, making it beneficial for acne scars and rough or uneven skin.
- Helps unclog pores and manage acne when used in lower concentrations.
- Used in both medical and cosmetic settings for medium-depth to deep chemical peels.
🧬Safety & Toxicology
- Should be administered by trained professionals, especially at concentrations above 20%.
- Can cause redness, peeling, swelling, burning, and temporary skin discoloration as part of the normal healing process.
- Overuse or incorrect application may result in burns, scarring, or post-inflammatory hyperpigmentation.
- Sun protection is critical during the recovery period to prevent further damage and pigmentation issues.
- Not suitable for all skin types; darker skin tones require caution due to higher risk of pigmentation changes.
- Non-carcinogenic and generally safe when used topically in controlled, professional settings.
- Should not be used on open wounds, active infections, or immediately before/after sun exposure.
See TCA Peels for treatment options.